What is Lipedema?.... A Brief Overview
- Sarah Cullen
- Mar 17
- 1 min read

What is Lipedema?
Lipedema is a chronic condition characterized by the abnormal accumulation of fat, primarily in the legs, thighs, buttocks, and sometimes the arms.
It mainly affects women and is often mistaken for obesity or lymphedema.
The fat buildup in lipedema is typically symmetrical (evenly distributed on both sides of the body) and does not respond to diet or exercise.
Characteristics of Lipedema

1. Symmetrical Fat Deposition
Unlike obesity, which usually involves generalized fat distribution, lipedema fat is symmetrically deposited in the legs, thighs, buttocks, and sometimes arms.
The feet and hands are not affected, creating a “cuffing” effect at the ankles or wrists.
2. Pain & Tenderness
Affected areas can be painful to the touch, even without external pressure.
Many individuals experience spontaneous pain, sensitivity, and easy bruising due to fragile blood vessels and connective tissue issues.
3. Progressive Swelling

Swelling increases as the day progresses and worsens in hot weather or after long periods of standing.
Unlike lymphedema, lipedema swelling does not involve fluid retention in the feet or hands (until later stages).
4. Skin Changes
The skin remains soft but may develop a nodular, bumpy texture (sometimes described as feeling like a "bean bag" or "orange peel").
In later stages, the skin may become firmer and harder due to fibrosis (hardening of connective tissue).
5. Limited Response to Diet & Exercise
Unlike typical obesity, lipedema fat is resistant to weight loss methods like calorie restriction and exercise.
Even individuals with a normal BMI can have lipedema.

